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Promising target for AIDS vaccine

A section of the AIDS virus's protein envelope once considered an improbable target for a vaccine now may be one of the most promising, new research by Dana-Farber Cancer Institute researchers...

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DNA of 50 breast cancer patients decoded

In the single largest cancer genomics investigation reported to date, researchers have sequenced the whole genomes of tumors from 50 patients with breast cancer and compared them to the matched DNA of...

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4 new genes identified for Alzheimer's

Mount Sinai School of Medicine scientists are part of a consortium that has identified four new genes that when present increase the risk of a person developing Alzheimer's disease during the later...

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Nurturing newborn neurons

Adult mice engineered to have more newborn neurons in their brain memory hub excelled at accurately discriminating between similar experiences � an ability that declines with normal aging and in some...

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Molecular probe to study disease

Chemical engineers at UC Santa Barbara expect that their new process to create molecular probes may eventually result in the development of new drugs to treat cancer and other illnesses. Their work,...

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First look at the mechanics of membrane proteins

In two new studies, scientists provide the first detailed view of the elaborate chemical and mechanical interactions that allow the ribosome � the cell's protein-building machinery � to insert a...

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A better mouse model to study depression

Scientists at the University of Pittsburgh School of Medicine have developed a mouse model of major depressive disorder (MDD) that is based on a rare genetic mutation that appears to cause MDD in the...

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Snapshots of Huntington's disease protein

Scientists at the Department of Energy's Oak Ridge National Laboratory and the University of Tennessee have for the first time successfully characterized the earliest structural formation of the...

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What is a laboratory mouse?

Mice and humans share about 95 percent of their genes, and mice are recognized around the world as the leading experimental model for studying human biology and disease. But, says Jackson Laboratory...

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Source of key brain function

Researchers at the University of Southern California have pinned down the region of the brain responsible for a key survival trait: our ability to comprehend a scene�even one never previously...

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New generation asthma drug could improve metabolism

Formoterol, a new generation asthma medication, shows great promise for improving fat and protein metabolism, say Australian researchers, who have tested this effect in a small sample of men. The...

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Finding genetic mistakes that fuel cancer

A dramatically better computer tool for finding the genetic missteps that fuel cancer has been developed by St. Jude Children's Research Hospital � Washington University Pediatric Cancer Genome...

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We are all mutants

Each one of us receives approximately 60 new mutations in our genome from our parents. This striking value is published in the first-ever direct measure of new mutations coming from mother and father...

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'Good' prion-like proteins boost immune response

A person's ability to battle viruses at the cellular level remarkably resembles the way deadly infectious agents called prions misfold and cluster native proteins to cause disease, UT Southwestern...

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New half-match bone marrow transplant

Half-matched bone marrow or stem cell transplants for blood cancer patients have typically been linked to disappointing clinical outcomes. However, a clinical trial conducted at the Kimmel Cancer...

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